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1 But these individuals, who are carriers, are also at a higher risk of progressing to an infection. diff may colonize the bowel as part of the normal gut microbiota but will not produce toxins and, therefore, will not cause symptoms. In approximately 3% of healthy adults and 14–71% of healthy babies C. diff may become an opportunistic pathogen, multiplying rapidly in the gut and producing toxins that cause intestinal conditions, such as diarrhea or colitis. For example, any of the following may lead to increased risk of infection: being 65 years or older, having recently stayed in a hospital, or having a compromised immune system. diff infection (CDI), other risk factors exist. While antibiotic treatment is often the most common predisposition for a C. diff Awareness Month by the Centers for Disease Control and Prevention (CDC). diff’s continuing status as a major cause of healthcare-associated infections (HAIs), the month of November has been designated C. diff causes approximately 500,000 infections per year in the United States, with approximately 29,300 of the infections resulting in death. This disruption can affect important immunoregulatory and metabolic functions, turning a relatively unnoticed organism into a harmful pathogen, raising serious healthcare concerns. However, some individuals who are taking antibiotics, particularly for long periods of time, experience disturbances in their normal balanced gut flora (microbiota) due to the antibiotics’ inadvertent killing of protective bacteria. In general, it doesn’t raise serious concerns for healthy individuals. diff, is a common microorganism found in the environment. The bacterium Clostridioides difficile, which was formerly named Clostridium difficile and is now commonly known as C.

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